Serum ferritin^‡ reduction

• In the clinical trial, 50% of patients experienced at least a 20% reduction in serum ferritin within 1 year of therapy.^1,2

Heart iron reduction

• In the clinical trial, there was an increase in cardiac MRI T2* from a mean at baseline of 11.8±4.9 ms to a mean of 15.1±7.0 ms after approximately 1 year of treatment.^1,12†

Liver iron reduction

• In the clinical trial, 42% of patients experienced at least a 20% reduction in liver iron within 1 year of therapy (95% CI, 32%-51%).^2†